Things happen; you just have to accept it.
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That is just how things go, and you can't change it.
When you say that's the way the cookie crumbles, you accept a bad turn as part of life.
It is used to shrug off a letdown with a calm, slightly weary air.
"That's Life"
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A general acceptance that difficult things happen as part of living
"Such Is Life"
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An expression of resigned acceptance toward an unfortunate situation
"That's the Way the Cookie Crumbles"
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Accepting a specific bad outcome with a shrug — that is just how it turned out