Vanished, wasted or failed completely.
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Lost or ruined completely.
When plans go up in smoke, everything you put in disappears with nothing to show.
People say it about money, hopes, or hard work.
"Down the Drain"
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Wasted or lost with no return, often used for money or effort that produced nothing
"Go Up in Flames"
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Being destroyed suddenly and dramatically, often with more intensity than going up in smoke
"Up in Smoke"
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Being completely ruined or lost, especially plans or investments that fail entirely