Crazy or insane.
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Acting in a crazy or completely irrational way.
When you say someone is off their rocker, you mean they are being totally unreasonable or out of their mind.
It's informal and often used humorously.
"Not Playing with a Full Deck"
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Lacking good judgment rather than acting dramatically irrational
"Out of Your Mind"
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Doing something surprisingly reckless, without the humorous tone
"Off Your Rocker"
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Behaving in a wild, irrational, or completely unreasonable way