To begin a journey or leave a place.
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To leave or start a journey.
When you hit the road, you're getting ready to go or you're already on your way.
It's an upbeat phrase for someone eager to leave or a group ready to move.
"Make Tracks"
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Leave quickly, with a sense of urgency
"Put Down Roots"
—
Settle permanently in a place and build a life there
"Hit the Road"
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Leave a place or start traveling somewhere