To do something that you can never undo.
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To make a decision or take an action you cannot undo.
When you cross the Rubicon, you commit yourself fully, knowing you cannot go back to where you started.
The phrase comes from Julius Caesar's fateful decision to cross the Rubicon River in 49 BC, which started a civil war.
"Burn Your Bridges"
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To permanently damage a relationship or future opportunity
"Take the Plunge"
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To commit to a risky decision after a period of hesitation
"Cross the Rubicon"
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A final, permanent commitment with no way to turn back